DENG Qi-hong, WANG Zheng, DENG Xian-ming, LI Li. Research progress on STAT protein inhibitors in the treatment of lymphomaJ. Acta Pharmaceutica Sinica, 2021, 56(3): 703-710. DOI: 10.16438/j.0513-4870.2020-1831
Citation: DENG Qi-hong, WANG Zheng, DENG Xian-ming, LI Li. Research progress on STAT protein inhibitors in the treatment of lymphomaJ. Acta Pharmaceutica Sinica, 2021, 56(3): 703-710. DOI: 10.16438/j.0513-4870.2020-1831

Research progress on STAT protein inhibitors in the treatment of lymphoma

  • The abnormal activation and mutation of signal transducer and activator transcription (STAT) proteins has been implicated in multiple lymphomas. The research discovery and clinical application of STATs inhibitors have become an important strategy for treating lymphoma. This review introduces the abnormal activation and mutation of STATs in multiple malignant lymphomas, and focuses on reviewing the latest screening strategies targeting STATs and its clinical application in the treatment of lymphoma, providing references for the further development of STATs inhibitors.
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