LI Xian-fu, ZHANG Zhi-wei, HONG Xiao-xuan, HAN Xiao-lu, LI Meng, WANG Zeng-ming*, ZHENG Ai-ping*. Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery systemJ. Acta Pharmaceutica Sinica, 2021,56(6): 1591-1598. doi: 10.16438/j.0513-4870.2020-1882
Citation: LI Xian-fu, ZHANG Zhi-wei, HONG Xiao-xuan, HAN Xiao-lu, LI Meng, WANG Zeng-ming*, ZHENG Ai-ping*. Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery systemJ. Acta Pharmaceutica Sinica, 2021,56(6): 1591-1598. doi: 10.16438/j.0513-4870.2020-1882

Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system

  • The efficient and safe delivery of drugs to the therapeutic site through the biofilm has traditionally been a difficult and hot topic in the field of drug delivery. In recent years, alkyl polyglycoside (APG) have become ideal penetration enhancers for drug delivery systems because of their high permeability, good safety and biodegradability, which has attracted wide attention of domestic and foreign researchers. In this paper, the physical and chemical properties, characteristics, action mechanism and application of APG in drug delivery system are reviewed, and its application prospect in drug delivery system is prospected.
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