GAO Pan-pan, REN Ya-ting, MA Jie, ZANG Ying-da, YANG Jing-zhi, ZHANG Dan, LI Chuang-jun*, ZHANG Dong-ming*. Two new labdane diterpenoids from the leaves of Callicarpa formosana RolfeJ. Acta Pharmaceutica Sinica, 2022,57(5): 1448-1451. doi: 10.16438/j.0513-4870.2021-1856
Citation: GAO Pan-pan, REN Ya-ting, MA Jie, ZANG Ying-da, YANG Jing-zhi, ZHANG Dan, LI Chuang-jun*, ZHANG Dong-ming*. Two new labdane diterpenoids from the leaves of Callicarpa formosana RolfeJ. Acta Pharmaceutica Sinica, 2022,57(5): 1448-1451. doi: 10.16438/j.0513-4870.2021-1856

Two new labdane diterpenoids from the leaves of Callicarpa formosana Rolfe

  • Two new labdane diterpenoids were isolated from 95% ethanol extract of the leaves of Callicarpa formosana Rolfe by using silica gel column, MCI column, ODS column and HPLC. Their structures were elucidated by HR-ESI-MS, NMR and ECD spectral data. All of them are new compounds, named 13E-6β-hydroxylabda-8(17),13-dien-15-oic acid (1) and 13E-7α-hydroxylabda-8(17),13-dien-15-oic acid (2). Compounds 1 and 2 were tested for antioxidant activity, and none of them had obvious activity.
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