A new guaiane-sesquiterpenoid from the leaves of Chimonanthus nitens Oliv.

Nine compounds were isolated from the leaves of Chimonanthus nitens Oliv. by silica gel, ODS, Sephadex LH-20 column chromatography and semi-preparative HPLC. They were identified as chimnitensene B (1), 1α-hydroxyisodauc-4-en-15-al (2), trans-4, 5-dihydroxycorocalane (3), trefoliol B (4), oplopanone (5), oplodiol (6), 3-(3'-hydroxybutyl)-2, 4, 4-trimethylcyclohexa-2, 5-dienone (7), 9(S)-4-oxo-7, 8-dihydro-β-ionol (8), and saniculamoid D (9) respectively, by MS, NMR and single crystal diffraction. Among them, compound 1 is a new guaiane-sesquiterpenoid, and compounds 2-9 were isolated from this plant for the first time.