LI Kai-zhi, YANG Shu-ping, LU Bo-tao, ZHU Yue-tong, LIU Shuang-jing, FENG Wei-sheng, WANG Yan-zhi. Isolation and identification of two new compounds from Semen PersicaeJ. Acta Pharmaceutica Sinica, 2023, 58(5): 1288-1292. DOI: 10.16438/j.0513-4870.2022-1306
Citation: LI Kai-zhi, YANG Shu-ping, LU Bo-tao, ZHU Yue-tong, LIU Shuang-jing, FENG Wei-sheng, WANG Yan-zhi. Isolation and identification of two new compounds from Semen PersicaeJ. Acta Pharmaceutica Sinica, 2023, 58(5): 1288-1292. DOI: 10.16438/j.0513-4870.2022-1306

Isolation and identification of two new compounds from Semen Persicae

  • Five compounds were isolated from the ethyl acetate fraction of Semen Persicae by using various chromatographic methods, including ODS, Sephadex LH-20, HPLC and semipreparative HPLC. Their structures were identified by 1D-NMR, 2D-NMR, HR-ESI-MS, UV, IR, circular dichroism (CD) and ECD calculation techniques: (2R, 3R)-5, 7, 4′-trihydroxy-3′-methoxy-3-formylflavan-3-ol-5-O-β-D-glucopyranoside (1), (7R, 8S)-dihydrodehydrodiconiferyl 6″-benzoyl alcohol-9-O-β-D-glucopyranoside (2), (7R, 8S)-dihydrodehydrodiconiferyl alcohol-9-β-O-D-glucopyranosid (3), 2-methoxy-4-(2-propenyl)-phenyl-O-β-D-glucopyranoside (4), 2-4-(3-hydroxypropyl)-2-methoxyphenoxy-propane-1, 3-diol (5). Compound 1 and 2 are new compounds, and compounds 3-5 were obtained from Prunus davidiana (Carr.) Franch. for the first time.
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