WANG Li-ke, LI Bing-yan, ZHAO Zhen-zhu, WANG Yan-zhi, LI Xiao-kun, FENG Wei-sheng, SI Ying-ying. A new glycoside from Alstonia mairei Lévl.J. Acta Pharmaceutica Sinica, 2025, 60(1): 191-195. DOI: 10.16438/j.0513-4870.2024-0737
Citation: WANG Li-ke, LI Bing-yan, ZHAO Zhen-zhu, WANG Yan-zhi, LI Xiao-kun, FENG Wei-sheng, SI Ying-ying. A new glycoside from Alstonia mairei Lévl.J. Acta Pharmaceutica Sinica, 2025, 60(1): 191-195. DOI: 10.16438/j.0513-4870.2024-0737

A new glycoside from Alstonia mairei Lévl.

  • Nine compounds were isolated and purified from 90% ethanol extract of Alstonia mairei Lévl by using various chromatographic methods, including silica gel, SephadexLH-20, MCI Gel and ODS column chromatography, combined with semi-preparative liquid phase separation methods. Modern spectroscopic methods (1D and 2D NMR, UV, IR, MS, etc.) were used to identify the structures of the isolated compounds. They were identified as mairoside A (1), 3′, 6-di-O-sinaloylsucrose (2), myristic acid (3), methyl myristate (4), ethyl myristate (5), 3, 4, 5-trimethoxycinnamic acid (6), 3, 4, 5-trimethoxybenzoic acid (7), vinoline (8), kaempferol-3-O-rutinoside (9), among which compound 1 is a new glycoside, compounds 4 and 5 are new natural products, and the nuclear magnetic data of compound 4 were reported for the first time.
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