Research progress in the application of microneedles drug delivery system in infectious wounds

Wound healing caused by skin trauma and chronic diseases is often complicated and difficult due to infection. In such cases, the wound healing process is not only a long and continuous one, but also prone to scar repair. Conventional dressings and antibiotic treatments suffer from issues such as low drug delivery efficiency and systemic toxicity. In recent years, microneedle technology has been widely used to reduce infection and promote wound healing. Microneedles can not only penetrate the skin stratum corneum and biofilm to enhance drug delivery efficiency and reduce drug side effects, but also can be combined with a variety of materials to achieve multiple treatments and monitoring of wounds. This article will discuss the healing mechanism of infected wounds, the classification of microneedles, and their applications in the treatment of infected wounds.