Lin Mulan, Liu Yufeng, Lu Yongyu, Zhang Huiqin , Zheng Weimin, . STUDIES ON ANTIARRHYTHMICS——SYNTHESIS OF 2-(ALKYLAMINO) METHYL-AND2,6-BIS-(ALKYLAMINO) METHYL-4-SUBSTITUTED AMINO PHENOLSJ. Acta Pharmaceutica Sinica, 1981, 16(10): 757-761.
Citation: Lin Mulan, Liu Yufeng, Lu Yongyu, Zhang Huiqin , Zheng Weimin, . STUDIES ON ANTIARRHYTHMICS——SYNTHESIS OF 2-(ALKYLAMINO) METHYL-AND2,6-BIS-(ALKYLAMINO) METHYL-4-SUBSTITUTED AMINO PHENOLSJ. Acta Pharmaceutica Sinica, 1981, 16(10): 757-761.
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STUDIES ON ANTIARRHYTHMICS——SYNTHESIS OF 2-(ALKYLAMINO) METHYL-AND2,6-BIS-(ALKYLAMINO) METHYL-4-SUBSTITUTED AMINO PHENOLS

    Abstract
  • Based on the fact that certain antimalarials containing 2-(alkylamino) methyl-4-aminophenol group or 2,6-bis (alkylamino) methyl-4-aminophenol group possess antiarrhythmic properties, a series of title compounds were synthesized. Preliminary pharmacological tests showed that some of these compounds were effective against aconitine-induced experimental arrhythmia in rats.
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