Advances in the study of nitric oxide-donating drugs

Nitric oxide (NO) as a messenger and/or effector plays important roles in vivo.  The decreased availability of NO or dysfunction in NO signaling has often been implicated in the development and progression of diseases, and design and research of NO-donating drugs has become one of the important strategies in drug discovery.  In connection with authors’ scientific practice, this article reviews the recent advances in the     research of NO-donating drugs.