STUDIES ON LIPOSOLUBLE CONSTITUENTS FROM THE AERIAL PARTS OF SIEGESBECKIA ORIENTALIS L.

Eight compounds were isolated from the aerial parts of Siegesbeckia orientalis L. and their structures were elucidated by spectroscopic methods(IR, EI-MS,¹³C-NMR, ¹H-NMR,¹H-¹H-COSY, ¹H-¹H-NOESY and ¹H-¹³C-COSY). Compounds I and II are new natural products and named siegesesteric acid(I) and siegesetheric acid(II), their structures were confirmed as ent-17-acetoxy-18-isobutyryloxy-16(α)-kauran-19-oic acid(I) and ent-17-ethoxy-16(α)-(-)-kauran-19-oic acid(II). The others were identified as known compounds: ent-16β, 17-dihydroxy-kauran-19-oic acid(III), kirenol(IV), β-sitosteryl glucoside(V), heneicosanol(VI), methyl arachidate(VII) and β-sitosterol(VIII). These compounds, except kirenol and β-sitosterol, were isolated for the first time from the title plant.