Application of HPLC/ELSD fingerprint and constellation graphical clustering method applied to evaluate the quality of Qingkailing injection
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Abstract
AimTo evaluate the quality of Qingkailing injections effectively, and to develop a credible method for the quality control of traditional Chinese medicine. MethodsFingerprints of 18 Qingkailing injection samples from various manufacturers were obtained by HPLC/ELSD, and quality evaluation was performed by constellation graphical clustering method. ResultsHPLC/ELSD and constellation graphical clustering method properly revealed the quality information apparently and accurately. ConclusionIt was an apparent, credible and efficient method for quality evaluation of Chinese medicines.
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