C21 STEROIDAL CONSTITUENTS FROM CYNANCHUM HANCOCKIANUM
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Abstract
Two new compounds hancogenin B(Ⅴ) and hancoside A (Ⅵ) and four knowncompounds glucogenin C (Ⅰ), cynatratoside A (Ⅱ), glaucogenin A (Ⅲ) and anhydrohirundigenin(Ⅳ) were isolated from the roots of Cynanchum hancockianum (Maxim) Al. Iljinski. Their structureswere identified on the basis of spectral evidence. The fragmentation ways of 13:14, 14:15-sec-opregnenes in EIMS were outlined and the antitumor activity of Ⅱ and the antiendotoxic activity of Ⅵwere also preliminarily tested in vitro.
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