SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α<sub>1</sub>-ADRENERGIC RECEPTOR

PQ Huang; B Rouot; R Wylde; B Castro

PQ Huang, B Rouot, R Wylde, B Castro. SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTORJ. Acta Pharmaceutica Sinica, 1992, 27(11): 864-866.

Citation:

PQ Huang, B Rouot, R Wylde, B Castro. SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTORJ. Acta Pharmaceutica Sinica, 1992, 27(11): 864-866.

Citation:

PQ Huang, B Rouot, R Wylde, B Castro. SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTORJ. Acta Pharmaceutica Sinica, 1992, 27(11): 864-866.

SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α₁-ADRENERGIC RECEPTOR

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Abstract

A new and high-yielding procedure was described for the synthesis of 4-amino-6,7-dimethoxy-24-4 (4-aminophenyl) butanoyl-1-piperazinyl-quinazoline Ⅶ, the key intermedi-ate for the newly designed potential α₁-AR affinity/photoaffinity probes Ⅷa/Ⅸa.

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SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTOR

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SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α₁-ADRENERGIC RECEPTOR