THE OPTICAL ROTATORY DISPERSION OF SOME SYNTHETIC INTERMEDIATES OF QINGHAOSU (ARTEANNUIN)

In this paper, the ORD and sector projection of 6 synthetic γ-lactone intermediates of Qinghaosu(Arteannuin) are reported. By-using ketone octant rule, lactone chirality rule and lactone sector rule, the predicted cotton effects of these compounds coincided with the result of determination and so the absolute configurations were assigned.