CHEMICAL STUDIES ON THE CONSTITUENTES OF PHYLLANTHUS URINARIA L.

Two new phenolic compounds(crystal Ⅵ and crystal Ⅸ) have been isolated from Phyllanthus urinaria L. (Euphorbiaceae). Their structures were determined by analysis of their UV, IR, ¹H-NMR, ¹H-¹H COSY, ¹³C-¹H COSY, long range ¹³C-¹H COSY, DEPT, EIMS and HREIMS spectral data. Crystal Ⅵ was determined as methyl brevifolincarboxylate. Crystal Ⅸ was elucidated as trimethyl ester dehydrochebulic acid. All of the signals of the ¹³C-NMR of these two new compounds have been assigned mainly according to DEPT, ¹³C-¹H COSY and long range ¹³C-¹H COSY. Accompanying these two new compounds, 8 known compounds have been isolated. By using chemical reactions,UV,IR,¹H-NMR,MS,their structures were elucidated as n-octadecane(Ⅰ), β-sitosterol(Ⅲ), ellagic acid (Ⅳ), daucosterol(Ⅴ), kaempferol (Ⅶ), quercetin (Ⅷ), gallic acid (Ⅹ) and rutin (Ⅺ). Crystal Ⅱ is an aldehyde, its structure elucidation is in progress.