PROTECTIVE EFFECT OF SALVIANOLIC ACID A ON ISCHEMIA- REPERFUSION INDUCED INJURY IN ISOLATED RAT HEART

The protective effect of salvianolic acid A(Sal A )on cardiac ischemia- reperfusioninduced injury was studied on the isolated rat heart.The results indicate that SaL A can reduce theoccurence of ventricular fibrillation,decrease the cellular LDH leaking and reduce the concentration oflipid peroxidation preduct- MDA significantly in ischemia-reperfused cardiac tissue. The possiblemachenism in decreasing ischemia-reperfusion injury of Sal A was discussed.