SYNTHESIS AND ANTIFUNGAL ACTIVITIES OF 1-(1-SUBSTITUTEDPHENYL)-2-(1H-1,2,4-TRIAZOL OR BENZTRIAZOL-1-YL)-O-(SUBSTITUTEDBENZYL) ETHANOXIMES
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Abstract
Twenty-nine 1-(1-substituted phenyl)-2-(1H-1,2,4-triazol or benztriazol-1-yl)-O-(substituted benzyl) ethanoximes have been synthesized for the first time. Results of preliminary biological test in vitro show that most compounds have antifungal activities against most fungi tested. The antifungal activities of compounds T1,T4,T6,T11 ,T12 ,B1,B3,B4 and B6 are better than or comparable to the activities of the lead compound oxiconazole against some fungi.
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