DERIVATIVE SPECTROPHOTOMETRIC—SIGNAL MULTIPLIER METHOD AND ITS APPLICATION TO THE DETERMINATION OF ASPIRIN IN XIAOER TUISHAO PIAN

A Microcomputer was used to process the spectral data measured on a manual spectrophotometer (UV-7520) for the determination of aspirin and acetaminophen in Xiaoer Tuishao Pian, using the derivative spectrophotometric-signal multiplier method.The method is simple and rapid. The mean recovery (%) of aspirin was 99.74±0.46. Dual wavelength method was used for the determination of acetaminophen and the recovery was 99.54±0.52%.