Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum

The study on the buds of Jasminum officinale L. var. grandiflorum was carried out to look for anti-HBV constituents.  The isolation and purification were performed by HPLC and chromatography on silica gel, polyamide and Sephadex LH-20 column.  The structures were elucidated on the basis of physicochemical properties and spectral analysis.  Six iridoid glycosides were identified as jasgranoside B (1), 6-O-methy-catalpol (2), deacetyl asperulosidic acid (3), aucubin (4), 8-dehydroxy shanzhiside (5), and loganin (6).  Jasgranoside B (1) is a new compound.  Compounds 2−6 were isolated from Jasminum officinale L. var. grandiflorum for the first time.