MEASUREMENT OF COLCHICINE BY ANODIC VOLTAMMETRY WITH CARBON PASTE ELECTRODE

Colchicine is determined by anodic voltammetry using a carbon paste electrode (graphite powder:paraffin liquid=1.5:1) in 0.05 mol·L^-1 H₂SO₄, with a linear range of 4.0×10^-7～1.0×10 ^-3 mol·L^-1, detection limit 1×10^-7mol·L^-1. Two waves at 1.07 and 1.33 V vs SCE were observed in the anodic scan, peak potential is increased with pH. The raw material and tablets of colchicine have been analysed with good results.