Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth.

AimTo study the chemical constituents of Evodia rutaecarpa (Juss.) Benth. Methods The crude total alkaloids were enriched by acid-base treatment and solvent extraction. Isolation and purification were carried out by silica gel column chromatography and recrystallization etc. Structural determination of the pure compounds were based on physico-chemical properties and various spectral data analysis (¹HNMR, ¹³CNMR, UV, IR, ¹H-¹H COSY, HMQC, HMBC, ESIMS, HREIMS, NOESY). ResultsFourteen compounds were obtained from Evodia rutaecarpa, ten of them were identified as evodianinine (1), rutaecarpine (2), evodiamine (3), wuchuyuamide I (4), hydroxyevodiamine 5), limonin (6), daucosterol (7), triacontanoic acid (8), nonacosane (9) and β-sitosterol (10). ConclusionCompound 1 is a new alkaloid named evodianinine.