STUDIES ON THE CHEMICAL CONSTITUENTS OF LYCIANTHES BIFLORA

AIMTo study the chemical constituents of Lycianthes biflora. METHODSColumn chromatography was used to separate the chemical constituents. IR, MS, 1HNMR, ¹³CNMR and 2D-NMR technique were used to determine the structures of the isolated constituents. RESULTSFive compounds were isolated from this plant. Their structures were identified to be bifloride A (1), N- trans-cinnamoyltyramine (2), liquiritigenin (3), N-trans-p-coumaroyloctopamine (4), 1-O-β-D-glucopyranosyl-2-N-2′-hydroxypalmitoyl-sphinga-4-trans-8-trans-dienine (5). CONCLUSIONCompounds 1 and 2 are new compounds, the others were isolated from this plant for the first time. Compound 2 showed inhibitory effects on P-388.