ALKALOIDS FROM THE ROOTS OF STEMONA TUBEROSA

AIM: Isolation and structural identification of alkaloids from the roots of Stemona tuberosa Tour, collected in Hebei province, North China. METHODS: The crude alkaloids was extracted by using cold EtOH percolation. The structures were identified by IR, MS as well as various 2D NMR spectra including proton line broadening effect. RESULTS: Four alkaloids, namely tuberostemoenone (1), tuberostemonone (2), didehydrotuberostemonine (3) and oxotuberostemonine (4) were isolated. CONCLUSION: Tuberostemoenone is a new alkaloid with novel skeletone.