CHEMICAL CONSTITUENTS OF DIURANTHERA INARTICULATA

AIM To investigate the chemical constituents from the roots of Diuranthera inarticulata Wang et K.Y.Lang. METHODS The compounds were isolated with silica gel column chromatography and their structures were identified on the basis of spectral data and TLC with authentic samples. RESULTS From the methanolic extracts of the roots of Diuranthera inarticulata, ten compounds were obtained and nine of them were identified as chloromaloside A (III), diuranthoside A (IV), diuranthoside B (V), diuranthoside F (VI), diuranthoside G(VII), 2α,3α,19α-trihydroxy-urs-12-en-28-oic acid (VIII), 3,6,7,3′,4′-pentamethoxy flavone (IX), gitogenin (X) and daucosterol (XI). III-VI showed inhibition of growth with the yeast,Candida albicans. III, IV and VI also showed inhibition of growth with fungus,Aspergillus niger, in the test of antibacterial activity. CONCLUSION All of these compounds were isolated from this plant for the first time. Among them, VI and VII are new steroidal saponins.