YE Xian-rong, YAN Ke-xu, WU Ke-mei, FENG Xiao-zhang, HUANG Yu-ming, QIU Ping. Synthesis and anti-inflammatory analgesic activities of sinomenine derivativesJ. Acta Pharmaceutica Sinica, 2004, 39(3): 180-183.
Citation: YE Xian-rong, YAN Ke-xu, WU Ke-mei, FENG Xiao-zhang, HUANG Yu-ming, QIU Ping. Synthesis and anti-inflammatory analgesic activities of sinomenine derivativesJ. Acta Pharmaceutica Sinica, 2004, 39(3): 180-183.
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Synthesis and anti-inflammatory analgesic activities of sinomenine derivatives

    Abstract
  • AimTo provide basic data for the synthesis of new sinomenine derivatives. MethodsThe C ring in sinomenine was modified. ResultsSeven compounds were prepared and screened for anti-inflammatory and analgesic activities. Compounds 2 and 5 showed better activities. ConclusionModification of the C ring in sinomenine should be worthy to be studied further.
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