Isolation and structural identification of chemical constituents from Selaginella tamariscina (Beauv.) Spring

AimTo study the chemical constituents of the water-extracts of Selaginella tamariscina (Beauv.) Spring. MethodsVarious chromatographic techniques were used to separate and purify the constituents. Their physico-chemical properties and spectral data were used to elucidate the structures. Results Nine compounds were isolated and identified as (2r,3s)-dihydro-2-(3′,5′-dimethoxy-4′-hydroxyphenyl)-7-methoxy-5-acetyl-benzofuran (1), 3-hydroxy-phenpropionic acid-(2′-methoxy-4′-carboxy-phenol) ester (tamariscina ester A, 2), sygringaresinol (3), 1-(4′-hydroxyl-3′-methoxyphenyl)glycerol (4), ferulic acid (5), caffeic acid (6), vanillic acid (7), syringic acid (8), and umbelliferone (9). ConclusionCompound 1 and 2 are new compounds, and the others were isolated from Selaginella for the first time.