COMMENTS ON “AN IMPROVEMENT ON THE WAGNER-NELSON METHOD FOR COMPUTING DRUG ABSORPTION RATE CONSTANT”
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Abstract
Some comments are made on the article "An Improvement on the Wagner—Nelson Method for computing Drug Absorption Rate Constant" (Acta Pharmaceutica Sinica 15:109,1980) The accuracy of Ka calculated according to the method can not be definitely improved either by taking more samples near the time when blood levels approach the characteristic yalues, or by simulating a quadratic parabola.
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