STUDIES ON CHEMICAL CONSTITUENTS OF TINOSPORA HAINANESIS

Tinospora hainanesis is a new species of Menispermaceae plant. It is used as folk remedy for joint pain and physical injury.Five compounds were isolated from the vine stalk of Tinospora hainanesis. By spectral analysis and chemical methods, the structures of the compounds were identified as makisterone A (I), 2,3-dimethoxy-9,10-dihydroxy-N-methyltetrahydroprotoberberine quaternary salt (II), palmatine (III), β-amyrin (IV) and docosyl ferulate (V). II is a new quaternary alkaloid named as haitinosporine. I, IV and V were isolated for the first time from the plants of Tinospora genus.