Electrochemical behavior of daunorubicin at Co/GC ion implantation modified electrode and the application of the electrode

AimTo study the electrochemical behavior of daunorubicin at Co/GC ion implantation modified electrode. MethodsWith Co/GC ion implantation modified electrode as working electrode, daunorubicin was determined by voltammetry in 0.05 mol·L^-1 Na₂HPO₄-KH₂PO₄(pH 6.82) solution. ResultsA sensitive reductive peak of daunorubicin was obtained by linear sweep voltammetry. The peak potential was -0.60 V (vs SCE)。The peak current was proportional to the concentration of daunorubicin over the range of 2.84×10^-8-1.42×10^-6 mol·L^-1 and 1.42×10^-6-1.28×10^-5 mol·L^-1 with the detection limit of 1.42×10^-8 mol·L^-1。The reduction wave was applied to the determination of daunorubicin. The electrochemical behavior and reaction mechanism were studied by linear sweep and cyclic voltammetry. ConclusionThe reduction process was quasi-reversible with adsorption characteristics.