STUDIES ON THE CHEMICAL CONSTITUENTS OF SECURIDACA INAPPENDICULATA

AIMTo investigate the chemical constituents of Securidaca inappendiculata. METHODS Compounds were isolated by silica gel column chromatography and Medium Pressure Liquid Chromatography, respectively. Structures of the compounds were elucidated by chemical evidence and spectral (UV, IR, MS, ¹HNMR and ¹³CNMR) analysis. RESULTSEight compounds (1～8) were isolated and identified. Seven of them (2～7) are known compounds: oleanolic acid, P-hydroxytruxinic acid, P-coumaric acid, ethyl P-methoxycinnamate, uridine, β-sitosterol and daucosterol. One (1) is a new hemiterpenoic acid glycoside, named securiterpenoside. CONCLUSION A new hemiterpenoic acid glycoside, named securiterpenoside, was isolated from Securidaca inappendiculata Hassk. Seven known compounds were isolated from genus Securidaca for the first time.