TWO NEW COMPOUNDS OF RADIX POLYGONI MULTIFLORI PREPARATA

AIM: To investigate the chemical constituents of Radix Polygoni multiflori Preparata. METHODS: Compounds were isolated from the n-BuOH extract with column chromatography of silica gel, Sephadex, ODS, and compounds were identified on the basis of spectral analysis (IR, EI-MS, FAB-MS, ¹HNMR, ¹³CNMR, 2D-NMR) and phytochemical properties. RESULTS: Five compounds were isolated and identified as: physcion-8-O-β-D-glucopyranoside (Ⅰ), emodin-8-O-β-D-glucopyranoside (Ⅱ), torachrysone-8-O-β-D-glucopyranoside (Ⅲ), 6-methoxyl-2-acetyl-3-methyl-1,4-naphthoquinone-8-O-β-D-glucopyranoside (Ⅳ), 2,3,5,4′-tetrahydroxystilbene-2-O-(6″-O-acetyl)-β-D-glucopyranoside (Ⅴ). CONCLUSION: Ⅳ and Ⅴare two new compounds.