THE TRITERPENOIDS OF TRIPTERYGIUM WILFORDII

AIM: To study the active principles of Tripterygium wilfordii Hook f. METHODS: Various column chromatographies with silica gel were employed for the isolation and purification of the ingredients. Their structures were elucidated by spectral analysis. RESULTS: Eight triterpenoids were obtained and were identified as wilforlide A (1), wilforlide B (2), 3-epikatonic acid (3), cangoronine (4), regelin (5), salaspermic acid (6), 3-hydroxy-2-oxo-3-fridelen-20α-carboxylic acid (7) and a new compound triptotin C (3β-hydroxy-D∶B-friedoolean-5∶6 epoxy-29-oic acid) (8). CONCLUSION: Compound (8) was a new compound.