Z Xiang. JE Zhou, ZN Chen, LP Wang, HN Wang, TR Yao, JX Xie, GY Xu , DN Yl, . STUDIES ON SYNTHESIS OF BAOGONGTENG A——A NEW MYOTIC AGENTJ. Acta Pharmaceutica Sinica, 1989, 24(2): 105-109.
Citation: Z Xiang. JE Zhou, ZN Chen, LP Wang, HN Wang, TR Yao, JX Xie, GY Xu , DN Yl, . STUDIES ON SYNTHESIS OF BAOGONGTENG A——A NEW MYOTIC AGENTJ. Acta Pharmaceutica Sinica, 1989, 24(2): 105-109.
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STUDIES ON SYNTHESIS OF BAOGONGTENG A——A NEW MYOTIC AGENT

    Abstract
  • Baogongteng A, isolated from Eryeibe obtusifolia Benth., is a new tropane alkaloid used for treating glaucoma. Using synthetic 6β-acetoxy-tropinone as starting material, racemic Baogongteng A(8) was synthesized. Synthetic Baogongteng A also shows myotic activities in rabbits, but the potency is half of that of the natural product.
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