Mechanism of psoriasis generation in animal models

Psoriasis is a chronic inflammatory disease related to genome-wide and surroundings, it is important to develop a suitable animal model to research psoriasis pathogenesis and evolve pharmacotherapeutics.  With the development of transgenetic technology in the past few years, psoriasis virulence gene animal model become a hotspot.  Research of animal model of human psoriasis genes is reviewed in the paper.