ELUCIDATION OF THE CHEMICAL STRUCTURES OF TWO STEROID SAPONINS OF DIOSCOREA NIPPNICA MAKINO
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Abstract
A Chinese medicine, "Chuanlong Guanxin Ning", made from Dioscorea nipponica Makino, has been used to treat coronary arteriosclerosis. Two sparingly soluble steroid saponins were isolated and purified by means of column chromatography and recrystallization. IR, MS, TLC, HPLC and tests of their physicochemical constants showed that one of them is Dioscin and the other Gracillin.
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