CHEMICAL STUDIES ON ACTIVE PRINCIPLES OF VERATRUM STENOPHYLLUM I. STUDIES ON THE STRUCTURE OF STENOPHYLLINE B AS WELL AS IDENTIFICATION OF THE OTHER COMPONENTS

Fourteen constituents(Ⅴ₁～Ⅴ₁₄) were isolated from Veratrum stenophyllum Diels. Eight of them were identified as β-sitosterol (Ⅴ₁), lignoceric acid (Ⅴ₂), daucosterol(Ⅴ₅), veratroylzygadenine(Ⅴ₇), etioline(Ⅴ₈), angeloylzygadenine(Ⅴ₉), zygadenine(Ⅴ₁₁) and jervine(Ⅴ₁₃). Stenophylline B(Ⅴ₆) is a new compound. The weak alkaloidal fraction and Ⅴ₇ were shown to have significant activity in lowering blood pressure and heart rate in anesthetic cats and dogs.Studies in the structure of stenophylline B (Ⅴ₆) is reported in this paper.