STUDIES ON THE CHINESE DRUG, ACONIITUM SPP——ⅩⅪ. ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZ

Two new alkaloids, N-deacetylranaconitine, C₃₀H₄₂N₂O₈, mp 125～127℃; and Ndeacetylfinaconitine, C₃₀H₄₂N₂O₉, mp.121—123℃, and three known alkaloids, avadharidine, lycoctonine and N-deacetyllappaconitine have been isolated from the root of Aconitum finetianum Hand-Mazz.The chemical structures of N-deacetylranaconitine and N-deacetylfinaconitine were estabished by UV, IR, NMR and MS spectral data and chemical evidences.In animal experiments, N-deacetylranaconitine, N-deacetylfinaconitine and N-deacetyllappaconitine exhibited strong analgesic activity.