QC Chen, CQ Yang, CH ChaO, YG Ma, XN Li , WL Chen, . PHARMACOKINETICS AND BIOAVAILABILITY OF GLIPIZIDE CAPSULESJ. Acta Pharmaceutica Sinica, 1995, 30(6): 476-480.
Citation: QC Chen, CQ Yang, CH ChaO, YG Ma, XN Li , WL Chen, . PHARMACOKINETICS AND BIOAVAILABILITY OF GLIPIZIDE CAPSULESJ. Acta Pharmaceutica Sinica, 1995, 30(6): 476-480.
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PHARMACOKINETICS AND BIOAVAILABILITY OF GLIPIZIDE CAPSULES

    Abstract
  • The pharmacokinetics and bioavailability of glipizide were studied in 8 healthymaie volunteers after a single oral dose of 5 mg in capule or in tablet.The plasma levels of glipizldewere assayed by high performance liquid chromatography.The concentration—time curves of bothpreparations were fitted to a one compartment model.The pharmacokinetic parameters of glipizide incapsule and in tablet were shown in tables 2 and 3.The relative bioavailability of the capsule was109.9%compared with the tablet.
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