WJ Zhang, TH Zhou , YY Cui, . THE IN VITRO METABOLISM OF HAINANENSINE DERIVATIVE HH07A BYT LIVER MICROSOMESJ. Acta Pharmaceutica Sinica, 1997, 32(2): 116-120.
Citation: WJ Zhang, TH Zhou , YY Cui, . THE IN VITRO METABOLISM OF HAINANENSINE DERIVATIVE HH07A BYT LIVER MICROSOMESJ. Acta Pharmaceutica Sinica, 1997, 32(2): 116-120.
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THE IN VITRO METABOLISM OF HAINANENSINE DERIVATIVE HH07A BYT LIVER MICROSOMES

    Abstract
  • The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed for screening the metabolites from the microsomal incubation system. Two metabolites were found according to their UV spectra. One of them was extracted and purified with preparative HPLC and TLC, its chemical structure was identified by UV, IR, MS and NMR.
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