STUDIES ON THE CHEMICAL CONSTITUENTS OF THE LEAVES FROM ARTABOTRYS HEXAPETALUS

Artabotrys hexapetalus (annonaceae) is distributed in southern China. As a Chinese folk herb medicine, its root and fruits are used to treat malaria and scrofula, respectively. Two new flavonol glycosides, artabotryside-A (1), -B (2), three known flavonoids: taxifolin (3), 7-O-glucoluteolin (4), apigenin-7-O-apiosyl(1→2) glycoside (5), and two organic acid: succinic (6) and fumaric acid (7) have been isolated from the leaves of A.hexapetalus. The structures of 1 and 2 were elucidated as quercetin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinofuranoside (1) and kaempferol-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinofuranoside (2), respectively, on the basis of spectral analysis. The compounds 3 through 7 were found from A.hexapetalus for the first time.