SYNTHESIS OF STEROIDAL ANALOGS OF GASTRIN AND STUDY ON THEIR BIOACTIVITIES
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Abstract
Two types of compounds,steroidal and oligopeptida; compounds,all havinggastrointestinal activity,were conjugated with active ester method.Six steroid-oligopeptides weresynthesized,and their structures were confirmed by spectra and elemental analysis.Preliminary studyon theirbioactivities showed that all the title compounds had bioactivities and their duration of actionwere longer than the control sample.
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