Progress of the study of mechanism on drug induced kidney injury

Drug-induced nephrotoxicity is very common in both new drug development and clinic practice.  Various drugs can induce kidney injuries, including tubulointerstitial, glomerular and renal vascular disease.   To investigate the mechanism of drug induced nephrotoxicity is important for risk reduction of new drug    development, reasonable drug usage, early discovery and effective prevention/treatment of adverse effects in clinics.