OPTIMIZATION OF THE SOLVENT SYSTEM USED FOR THIN LAYER CHROMATOGRAPHY VI. FURTHERING OF THE UNIFORM DESIGN METHOD

In this paper, we optimized the solvent systems of sulfa drugs and five traditionalChinese medicines for thin layer chromatography by means of uniform design method. The optimal sys-tem for the eleven sulfa drugs is benzene--n-butanol--n-hexane (5. 71:2. 86:1.43). The optimalsystems for Mu Xiang and Jiu Li Xiang are all absolute chloroform. The optimal systems for LiangMian Zhen and San Cha Ku are all acetonitrile--ethyl ether--methyl chloride--cyclohexane (0. 05:0. 3:0.1 :0.55). The optimal system for Jin Yin Hua is ethyl acetate--methyl chloride--formic acid(1:1:1). The method has been born out to be theoretical, simple and practical. In our opinion, it isan effective systematic method.