STUDIES ON SAPONINS FROM THE LEAVES OF PANAX JAPONICUS VAR. BIPINNATIFIDUS(SEEM.)WU ET FENG

Two new saponins, bipinnatifidusoside F₁(Ⅻ) and F₂(ⅩⅢ), were isolated along with eleven known saponins from the dried leaves of Panax japonicus var.bipinnatifidus(Seem.)Wu et Feng collected in the Range of Qinling Mountains in China. By spectrometric analysis(FAB-MS,¹H and ¹³CNMR,¹H-¹H COSY), their structures were elucidated as dammar-25(26)-ene-3β, 12β, 20(S), 2ξ- tetraol-(20-O-β-D-glucopyranosyl)-3-O-β-D-glucopyranosyl(1-2)-β-D-glucopyranoside(bipinnatifidusoside F₁) and dammar-22(23) ene-3β,12β, 20(S), 24ξ-tetraol-(20-O-β-D-glucopyranosyl)-3-O-β-D-glucopyranosyl(1-2)-β-D-glucopyranoside (bipinnatifidusoside F₂), respectively. The known saponins were identified as ginsenoside F₁,F₂,F₃,Rg₂,Re,Rd,Rb₁,Rb₃, 24(S)-pseudoginsenoside F₁₁,panasenoside and majoroside F₁.Compared with bipinnatifidusoside F₂,majoroside F₃ was corrected as dammar-22 (23)-ene-3β,12β,20(S), 24ξ-tetraol-(20-O-β-D-glucopyranosyl)-3-O-β-D-glucopyranoside.