Recent advance in the study of novel anti-tumor targets and drugs —aurora kinase and Pin1

Malignant tumor, one of the most refractory diseases, plays a threaten role in human health, the therapy and research on malignant tumor have taken a long way to go.  The anti-tumor drugs which are the   essential therapy strategies upgrade with the development of new anti-tumor targets and the research on tumor pathogenesis.  Aurora kinase and Pin1, the novel anti-tumor targets, maintain the important relationship with tumor.  Many new compounds designed on these targets have excellent anti-tumor effects and also enter into phase I or phase II clinical trial.