Studies on the lignans from Patrinia scabra

AimTo study the lignans from Patrinia scabra Bunge. MethodsThe constituents were separated and purified by column chromatography with silical gel, RP-silical gel and Sephadex LH-20. Their structures were identified on the basis of spectral data (IR, MS, ¹HNMR, ¹³CNMR, HMQC and HMBC). Results and ConclusionA new lignan was obtained and its structure was elucidated as 4-［1-ethoxyl-1-(4-hydroxy-3-methoxy)benzyl］methyl-2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyl-tetrahydro-furan (2), along with three known lignans, lariciresinol (1)，isolariciresinol (3) and nortracheloside (4).