DETERMINATION OF ALLOPURINOL IN TABLETS AND URINE BY OSCILLOPOLAROGRAPHY

Determination method of allopurinol has been studied by the second derivative oscillopolarography. Well-defined linear relationship between concentrations and the wave height in the range 3×1^-7～1×10^-4mol/L and 5×10^-7～1×10^-4 mol/L was observed, respectively, in 0.50 mol/L H₂SO₄ and pH 5.5 HAc-NaAc buffer. The contents of allopurinol in tablets and urine were determined. The character of the electrode reaction was explored preliminarily.