Diterpenes constituents of Tripterygium wilfordii

AimTo study the chemical constituents of Tripterygium wilfordii Hook.F. Methods Various column chromatographies with silica gel were used for the isolation and purification. The structures of compounds were established on the basis of its IR, MS, UV, ¹H NMR, ¹³C NMR and HRMS, ¹H-¹H COSY, ¹H-¹³C COSY and NOESY. ResultsFour diterpenoids were isolated: 16-hydroxytriptolide (I), triptolidenol (II), tripdiolide (III), 2-epitripdiolide (IV). ConclusionCompound IV is a new diterpenoid.