Photo-degradation products of 1-［1-(6-methoxy-2-naphthyl)ethyl］-2-(4-nitrobenzyl)-6,7-dimethoxyl-1,2,3,4-tetrahydroisoquinoline hydrobromide

To study the photo-degradation products of 1-［1-(6-methoxy-2-naphthyl)ethyl］-2-(4-nitrobenzyl)-6,7-dimethoxyl-1,2,3,4-tetrahydroisoquinoline hydrobromide (code designation: P91024). The chemical structures of the major photo-degradation products of P91024 were identified by HPLC-MS and spectroscopic methods, and their reference substances were also synthesized for confirmation. The three major photo-degradation products were identified to be N-(4-nitrobenzyl)-6,7-dimethoxyl-3,4-dihydroisoquinoline bromide, 1-［1-(6-methoxyl-2-naphthyl)ethyl］-6,7-dimethoxyl-1,2,3,4-tetrahydroisoquinoline and 2-isopropyl-6- methoxyl-naphthalene, respectively.