SEPARATION AND IDENTIFICATION OF THE FLAVONOIDS FROM BUDDLEIA OFFICINALIS MAXIM

The flowers of Buddleia officinalis Maxim have been used to cure eyeinflammation in China.Eight flavonoid compounds were isolated from them.Their structures werecharacterized as acacetin(1),apigenin(2),luteolin(3),neobudofficide(4),linarin(5,acaciin),luteolin-7-O-rutinoside(6),luteolin-7-O-glucoside(7)and cosmosiin(8),on the basis of chemicaland spectral evidences.The new compound 4 was identified as 5,7-dihydroxy-4'-O-methoxyflavone-7-O-α-L-rhamnopyransoyl(1→2)-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside and namedneobudofficide.All the compounds were isolated from B.officinalis for the first time,except linarinand acacetin.